Omeprazole full prescribing information

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Discover the comprehensive details of Omeprazole, a trusted medication for gastric acid-related conditions. Trust the strength of Omeprazole for effective relief and long-lasting benefits. Take control of your digestive health with Omeprazole.

Indications and Usage

Omeprazole is a proton pump inhibitor (PPI) indicated for the following conditions:

Gastric and duodenal ulcers

  • Healing of gastric ulcers associated with Helicobacter pylori infection
  • Prevention of recurrence of peptic ulcers

Gastroesophageal reflux disease (GERD)

  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Symptomatic treatment of GERD

Omeprazole is also indicated for the treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome.

Indications and Usage

Omeprazole is indicated for the treatment of:

Gastroesophageal Reflux Disease (GERD) Healing of Erosive Esophagitis
Pathological Hypersecretory Conditions, Including Zollinger-Ellison Syndrome Maintenance of Healing of Erosive Esophagitis
Helicobacter pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence

Omeprazole is also used in combination with antibiotics for the treatment of Helicobacter pylori infection and duodenal ulcer disease.

Dosage and Administration

It is important to follow the recommended dosage and administration instructions for Omeprazole to ensure its effectiveness and safety.

Indication Dosage Administration
Gastroesophageal Reflux Disease (GERD) 20 mg once daily for 4-8 weeks Take before a meal
Helicobacter pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence 20 mg twice daily with amoxicillin and clarithromycin for 10 days Take with food
Pathological Hypersecretory Conditions, Including Zollinger-Ellison Syndrome 60 mg once daily May divide dose to be taken twice daily
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It is important to take Omeprazole as directed by your healthcare provider. Do not exceed the recommended dosage or frequency of administration without consulting a healthcare professional.

Warnings and Precautions

Omeprazole is a proton pump inhibitor and may increase the risk of gastrointestinal infections such as Clostridium difficile-associated diarrhea. Patients should be advised to seek medical attention if they experience severe diarrhea during or after treatment with omeprazole.

Long-term use of omeprazole may be associated with an increased risk of bone fractures, especially in the hip, wrist, or spine. Patients should discuss with their healthcare provider the potential risks and benefits of long-term omeprazole therapy, especially in those at high risk for osteoporosis.

Drug Interactions:

Drug Interactions:

  • Omeprazole may interact with other medications, such as warfarin, atazanavir, and clopidogrel. Patients should inform their healthcare provider about all the medications they are taking before starting omeprazole therapy.
  • Combining omeprazole with certain medications may reduce the effectiveness of omeprazole. It is important to consult with a healthcare professional before combining omeprazole with other medications.

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Adverse Reactions

Omeprazole may cause side effects in some individuals. Common adverse reactions include:

  • Headache
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea

If any of these side effects persist or worsen, it is important to consult a healthcare provider promptly. In rare cases, Omeprazole may cause severe allergic reactions such as rash, itching, swelling, dizziness, or difficulty breathing. If any of these symptoms occur, seek immediate medical attention.

How Supplied/Storage and Handling

Omeprazole is available in the form of delayed-release capsules containing 20 mg of omeprazole. Each bottle contains 30 capsules.

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Storage: Store omeprazole at controlled room temperature between 68°F to 77°F (20°C to 25°C). Protect from moisture and light. Keep the bottle tightly closed.

Handling: Handle omeprazole with care to avoid damaging the capsules. Do not crush or chew the capsules. Swallow the whole capsule with water. Keep omeprazole out of reach of children and pets.